Transcrestal maxillary sinus floor elevation represents an effective surgical option to vertically enhance the available bone in the edentulous posterior maxilla. The purpose of the present study is to describe a minimally invasive technique for transcrestal sinus floor elevation, the Smart Lift technique, through a paradigmatic clinical case. The Smart Lift technique is based on specially designed drills and osteotomes used with a stop device that restricts the working action to the residual bone, thus preventing the accidental penetration of instruments into the sinus cavity. Also, the use of a standardized sequence of instruments has been shown to limit the impact of the clinician’s judgement and skill, thus allowing for rapid learning for inexperienced clinicians. The technique is effective to achieve endo-sinusal bone formation with limited post-surgical morbidity.